At HPI Engine, we empower founders to build impactful ventures at the intersection of cutting-edge technology and real-world application. Our focus areas reflect the domains where we combine deep academic expertise with entrepreneurial experience, offering tailored support, research access, and practical guidance.
AI, Data & Machine Learning
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This focus area supports founders who push the boundaries of artificial intelligence, building intelligent, data-driven products. Ranging from generative AI and decision-support systems to predictive analytics and automation tools. With access to HPI’s cutting-edge labs, datasets, and expertise in scalable data architecture, applied machine learning, and language technologies, participants turn data into actionable insights and AI into scalable innovation.
Cybersecurity
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Building trust through secure software products is essential across all digital sectors. This area enables founders to build authentication systems, compliance platforms, secure communication tools, and other trust-critical technologies.Grounded in HPI’s leading research in IT security and data privacy, participants develop resilient products that meet the demands of modern digital infrastructures.
Offers in this focus area:
Potsdam Conference for National CybersecurityDigital Health & MedTech
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Software is reshaping medicine—from AI-assisted diagnostics to patient-centric platforms. This area leverages HPI’s extensive research and collaborations in digital health, supporting ventures that improve medical outcomes, enable system-level efficiencies, and enhance patient experience while meeting strict usability and interoperability standards.
Offers in this focus area:
Digital Health SparkEnterprise Tech
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Founders in this area develop software products that digitize and automate business processes, ranging from B2B SaaS platforms and workflow engines to vertical enterprise solutions. Building on HPI’s strengths in business process technology, cloud architecture, and integration systems, participants address challenges in productivity, interoperability, and digital transformation across industries.
Societal Impact
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We believe innovation has the power not only to drive economic growth but, more importantly, to create meaningful societal impact. Digital products in this area address education, civic engagement, digital participation, and accessibility. Typical business models include impact platforms, edtech applications, and civic tech tools. Founders work on mission-driven ventures, supported by research on human-centered design, digital learning, and governance technology.
Offers in this focus area:
Global Impact Sprint NYCSustainable Technologies & Climate Tech
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Climate action demands digital innovation. Entrepreneurial solutions in this area focus on emission tracking, resource optimization, and sustainable infrastructure. Startups work on software for carbon accounting, smart grids, green mobility, and resource optimization. Building on HPI’s applied research in energy informatics and environmental modeling, these innovations enable the transition to a more sustainable future.
Venture Capital Readiness
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We believe innovation has the power not only to drive economic growth but, more importantly, to create meaningful societal impact. Digital products in this area address education, civic engagement, digital participation, and accessibility. Typical business models include impact platforms, edtech applications, and civic tech tools. Founders work on mission-driven ventures, supported by research on human-centered design, digital learning, and governance technology.
Offers in this focus area:
HPI Venture Builder